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Dorsal subcoeruleus (SubCD) neurons are thought to promote PGO waves and to be modulated by cholinergic afferents during REM sleep. We examined the differential effect of the cholinergic agonist carbachol (CAR) on excitatory and inhibitory postsynaptic currents (PSCs), and investigated the effects of CAR on SubCD neurons during the developmental decrease in REM sleep.

Cholinergic Modulation of GABAergic and Glutamatergic Transmission in the Dorsal Subcoeruleus: Mechanisms for REM Sleep Control