Open AccessFocal And Global Brain Measurements in Siblings of Patients With Schizophrenia
Author(s) -
H. B. M. Boos,
Wiepke Cahn,
Neeltje E.M. van Haren,
Eske M. Derks,
Rachel M. Brouwer,
Hugo G. Schnack,
Hilleke E. Hulshoff Pol,
R.S. Kahn
Publication year - 2011
Publication title -
schizophrenia bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.823
H-Index - 190
eISSN - 1745-1701
pISSN - 0586-7614
DOI - 10.1093/schbul/sbq147
Subject(s) - schizophrenia (object oriented programming) , psychosis , neuroimaging , psychology , white matter , magnetic resonance imaging , brain disease , sibling , cerebellum , neuroscience , medicine , disease , psychiatry , developmental psychology , radiology
It remains unclear whether structural brain abnormalities in schizophrenia are caused by genetic and/or disease-related factors. Structural brain abnormalities have been found in nonpsychotic first-degree relatives of patients with schizophrenia, but results are inconclusive. This large magnetic resonance imaging study examined brain structures in patients with schizophrenia, their nonpsychotic siblings, and healthy control subjects using global and focal brain measurements.
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