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the supporting evidence, estimates of values and preferences, and resource use. Ultimately, guideline panels must use judgment in integrating these factors to make a strong or weak recommendation The use of this system has several advantages; it uses a transparent and explicit approach and is evidence based. GRADE is now the preferred quality of evidence rating system, and has been adopted by over 50 organizations worldwide.

rheumatology

18. Challenges in developing clinical practice guidelines for diagnostic tests: a systematic literature review of the use of imaging for the diagnosis of polymyalgia rheumatica