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of cervical cancer and underserved by national screening programmes. Conclusion: The rate of all malignancies in pts receiving long-term TCZ has remained stable over time. To date, there is no evidence of higher than expected malignancy risk in RA pts treated long-term with TCZ vs the general population. Disclosure statement: R.F.v.V. has received a consulting fee from Abbott, BMS, GSK, MSD, Pfizer, Roche and UCB; and has received a research grant from Abbott Immunology Pharmaceuticals, BMS, GSK, MSD, Pfizer, Roche and UCB. A.R.-R. has received a consultancy payment from Roche, Chugai, Pfizer, UCB and MSD; has been involved in a speakers’ bureau for Roche, UCB and MSD; and has received a research grant from Roche, Chugai and Pfizer. A.S. has received a consultancy payment from Genentech, Lilly, Novartis and Merck; and has been involved in a speakers’ bureau for Genentech and Novartis. B.P.-B. is and employee of Roche and has stock, stock options or bond holdings. L.R. is an employee of Roche and has stock, stock options or bond holdings. P.N. is an employee of Roche and has stock, stock options or bond holdings. D.S. is and employee of Roche.

rheumatology

95. Tocilizumab Inhibits Radiographic Progression And Improves Physical Function In Patients With Rheumatoid Arthritis At 5 Years With Maintenance Of Clinical Efficacy Over Time