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The positioning of secukinumab in the treatment of axial SpA (axSpA) and PsA is debated, partly due to a limited understanding of the comparative safety of the available treatments. We aimed to assess the risk of the key safety outcome infections during treatment with secukinumab and TNF inhibitors (TNFi).

Is the risk of infection higher during treatment with secukinumab than with TNF inhibitors? An observational study from the Nordic countries