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To investigate the effects of culture conditions, serum and specific cytokines such as insulin-like growth factor (IGF) 1 and interleukin (IL) 1alpha on phenotype and cell survival in cultures of Syrian hamster embryonic chondrocyte-like cells (DES4(+).2).

rheumatology

Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox‐9 transcription factor