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There is limited published scientific data on vaping recreational drugs other than cannabis. A recent review suggested that 15% of people vaping cannabis have also vaped a synthetic cannabinoid receptor agonist (SCRA) and identified over 300 Internet reports of e-liquid manufacture of recreational drugs and/or new psychoactive substances (NPS).

A cloud on the horizon–a survey into the use of electronic vaping devices for recreational drug and new psychoactive substance (NPS) administration