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Sir,Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease that affects mainly middle age women1,,2 with a slowly progression to cirrhosis. Little is known about the clinical expression of PBC in younger and elderly patients. We analysed the clinical profile of patients at presentation on the basis of the age at diagnosis.One hundred and ninety-eight patients who satisfied the established criteria for a diagnosis of PBC3 were included in this study and subdivided in three groups: group A (including patients with an age <45 years—44 cases), group B (with an age …

Clinical and serological profile of primary biliary cirrhosis in young and elderly patients