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Article Outline Abstract Introduction Patients and methods Procedure Statistical analysis Results Discussion Conclusion References Background Irritability is common in Attention deficit hyperactivity disorder (ADHD) which is sometimes associated with Mood symptoms. Results from community samples suggest that 4.3–23.5% of those with ADHD meet Disruptive mood dysregulation disorder diagnostic criteria. The Aim of this study: To compare the prognostic outcome of ADHD symptoms in ADHD children with comorbid mood disorders compared to those without comorbid mood disorders receiving non-stimulant medication. Patients and Methods This is An observational prognostic prospective study in which two groups of ADHD patients were included in the study, group 1 includes 40 ADHD patients without comorbid mood disorders and group 2 includes 40 ADHD patients with comorbid mood disorders, they were assessed using; The Kiddie Schedule for Affective Disorder and Schizophrenia for School Age Children Rating scales as Conners’ Parent Rating Scale-Revised Long Version, Pediatric behavior rating scale and Children Depression Inventory. Results ADHD symptoms (hyperactivity and inattention) were found to be improved regarding the hyperactivity in a statistically significant way in the mood group after 1 week of receiving non stimulant medications, while there was no significant change in the non-mood group, Also there was significant improvement of the inattention symptoms among the two groups after receiving non stimulant medication. Meanwhile severity of depressive symptoms showed an improvement in the mood group while there was no change in severity in the non-mood group. As regards the irritability symptoms it showed insignificant change in both groups among the two follow-ups. Conclusion There is a more significant decrease in inattention symptoms in ADHD children with comorbid mood disorder who received non-stimulant treatment for one week more than the children without comorbid mood disorder. Moreover the depressive symptoms decreases among patients with ADHD and mood disorders after one week of receiving non-stimulant treatment.

Follow up study on Attention Deficit Hyperactivity Disorder patients with and without comorbid mood disorders receiving Non Stimulant medication