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mechanical stimuli: cyclooxygenase-2, manganese superoxide Taylor WR. Cyclic strain induces an oxidative stress in endotheldismutase, and endothelial cell nitric oxide synthase are selectial cells. Am J Physiol 1997; 272: C421-427 ively up-regulated by steady laminar shear stress. Proc Natl 34. Jun T, Ke-yan F, Catalano M. Increased superoxide anion Acad Sci USA 1996; 93: 10417-10422 production in humans: a possible mechanism for the pathogen33. Howard AB, Alexander RW, Nerem RM, Griendling KK, esis of hypertension. J Hum Hypertens 1996; 10: 305-309

Goodpasture syndrome and end-stage renal failure-to transplant or not to transplant?