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The aim of the study was to test the efficacy of recombinant tissue plasminogen activator and streptokinase in massive pulmonary embolism, the primary endpoints being haemodynamic improvement and thrombus lysis, and the secondary endpoints efficacy and safety.

Streptokinase vs alteplase in massive pulmonary embolism: A randomized trial assessing right heart haemodynamics and pulmonary vascular obstruction