Open AccessCancer-testis specific gene OIP5: a downstream gene of E2F1 that promotes tumorigenesis and metastasis in glioblastoma by stabilizing E2F1 signaling
Author(s) -
He Jiang,
Yuzu Zhao,
Erhu Zhao,
Xianxing Wang,
Zhen Dong,
Yibiao Chen,
Liqun Yang,
Hongjuan Cui
Publication year - 2018
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/noy037
Subject(s) - carcinogenesis , e2f1 , cancer research , metastasis , biology , chromatin immunoprecipitation , e2f , transcription factor , cell growth , cell cycle , cancer , gene expression , gene , promoter , biochemistry , genetics
The cancer-testis specific gene Opa interacting protein 5 (OIP5) is reactivated in many human cancers, but its functions in glioblastoma remain unclear. Here, we assessed the significance of OIP5 in the tumorigenesis and metastasis of glioblastoma for the first time.
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