Soluble TACI and soluble BCMA as biomarkers in primary central nervous system lymphoma | Zendy

Franziska Thaler | Zendy; Sarah Laurent | Zendy; Marion Huber | Zendy; Matthias Mulazzani | Zendy; Martin Dreyling | Zendy; Uwe Ködel | Zendy; Tania Kümpfel | Zendy; Andreas Straube | Zendy; Edgar Meinl | Zendy; Louisa von Baumgarten | Zendy

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Soluble TACI and soluble BCMA as biomarkers in primary central nervous system lymphoma

Author(s) -

Franziska Thaler,

Sarah Laurent,

Marion Huber,

Matthias Mulazzani,

Martin Dreyling,

Uwe Ködel,

Tania Kümpfel,

Andreas Straube,

Edgar Meinl,

Louisa von Baumgarten

Publication year - 2017

Publication title -

neuro-oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.005

H-Index - 125

eISSN - 1523-5866

pISSN - 1522-8517

DOI - 10.1093/neuonc/nox097

Subject(s) - primary central nervous system lymphoma , primary (astronomy) , central nervous system , lymphoma , medicine , physics , astronomy

B-cell survival is regulated through interactions of B-cell-activating factor and a proliferation-inducing ligand with their receptors transmembrane activator and CAML interactor (TACI) and B-cell maturation antigen (BCMA). We evaluated the diagnostic potential of soluble TACI (sTACI) and soluble BCMA (sBCMA) in CSF and serum as biomarkers in primary CNS lymphoma (PCNSL).

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