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Chordomas are rare, locally aggressive bony tumors associated with poor outcomes. Recently, the single nucleotide polymorphism (SNP) rs2305089 in the T (brachyury) gene was strongly associated with sporadic chordoma development, but its clinical utility is undetermined.

neuro-oncology

Spinal column chordoma: prognostic significance of clinical variables and<i>T (brachyury</i>) gene SNP rs2305089 for local recurrence and overall survival

Spinal column chordoma: prognostic significance of clinical variables andT (brachyury) gene SNP rs2305089 for local recurrence and overall survival