A single-cell map for the transcriptomic signatures of peripheral blood mononuclear cells in end-stage renal disease
Author(s) -
Ting Luo,
Fengping Zheng,
Kang Wang,
Yong Xu,
Huixuan Xu,
Wenxi Shen,
Chengxin Zhu,
Xinzhou Zhang,
Weiguo Sui,
Donge Tang,
Lianghong Yin,
Yong Dai
Publication year - 2019
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfz227
Subject(s) - peripheral blood mononuclear cell , transcriptome , immune system , end stage renal disease , cell , cell type , biology , immunology , inflammation , single cell analysis , disease , medicine , computational biology , gene expression , genetics , gene , in vitro
Immune aberrations in end-stage renal disease (ESRD) are characterized by systemic inflammation and immune deficiency. The mechanistic understanding of this phenomenon remains limited.
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