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AND AIMS: Trimethylamine-oxide (TMAO) is a endogenously biosynthesized metabolite from trimethylamine, which is derived from phosphatidylcholine(lecithin) and carnitine. TMAO has been linked to adverse cardiovascular outcomes in the general population, however, the role of TMAO in dialysis patients remains to be elucidated. Therefore, we aimed to investigate the relationship between serum TMAO levels and cardiovascular events in hemodialysis(HD)patients.

SP538ASSOCIATION BETWEEN TRIMETHYLAMINE OXIDE AND CARDIOVASCULAR EVENTS IN HEMODIALYSIS PATIENTS