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Reduces Mediators of Vascular Calcification In Vitro and in CKD Patients Dean Gilham1, Laura Tsujikawa1, Sylwia Wasiak1, Chris Halliday1, Chris Sarsons1, Stephanie Stotz1, Kamyar Kalantar-Zadeh2, Ravi Jahagirdar1, Jan O. Johansson3, Norman CW Wong1, Mike Sweeney3, Richard Robson4, Ewelina Kulikowski1 Resverlogix Corp. 1Calgary, Canada and 3San Francisco, USA, 2University of California, Irvine, USA, 4Christchurch Clinical Studies Trust, Christchurch, New Zealand

FP294INHIBITION OF BET PROTEINS WITH APABETALONE REDUCES MEDIATORS OF VASCULAR CALCIFICATION IN VITRO AND IN CKD PATIENTS