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METHODS: 175 patients with IgA nephropathy from our hospital’s registry diagnosed between 2007. and 2015. were included in the study. Ultrasound guided kidney biopsy was performed on all patients and samples were analysed using light, immunofluorescent and electron microscopy. We measured glomerular basement membrane thickness and the values were standardised for our nephropathology laboratory: 340636 nm in males and 301644 nm in females. Clinical geneticist analysed family history of patients with TGBM for the presence of possible hereditary kidney diseases and/or microhematuria. Genome sequencing is being done in order to detect COL4a mutations in patients with positive family history. We present one patient with completed analysis.

FP194SERUM CYSTATIN C LEVEL INDICATES EARLY GLOMERULAR AND TUBULAR INTERSTITIAL LESIONS IN PATIENTS WITH PRIMARY GLOMERULONEPHRITIS