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apy on the glomerular filtration rate of the kidney: an exploratory trial. J Clin Periodontol 2010; 37: 638–643 32. ArteseHP, Sousa CO, Luiz RR et al. Effect of non-surgical periodontal treatment on chronic kidney disease patients. Braz Oral Res 2010; 24: 449–454 33. Inoue CN, Matsutani S, Ishidoya M et al. Impact of periodontal treatment in combination with tonsillectomy plus methylprednisolone pulse therapy and angiotensin blockade for pediatric IgA nephropathy. Clin Nephrol 2012; 77: 137–145 34. Wehmeyer MM, Kshirsagar AV, Barros SP et al. A randomized controlled trial of intensive periodontal therapy on metabolic and inflammatory markers in patients With ESRD: results of an exploratory study. Am J Kidney Dis 2013; 61: 450–458 35. Fang F,Wu B, Qu Q et al. The clinical response and systemic effects of nonsurgical periodontal therapy in end-stage renal disease patients: a 6-month randomized controlled clinical trial. J Clin Periodontol 2015; 42: 537–546 36. Jamieson L, Skilton M, Maple-Brown L et al. Periodontal disease and chronic kidney disease among Aboriginal adults; an RCT. BMC Nephrol 2015; 16: 181

Skeletal fractures in patients on renal replacement therapy: how large still is the knowledge gap?