Open AccessIncreased plasma dipeptidyl peptidase 4 activities predict new-onset microalbuminuria in association with its proinflammatory effects in Chinese without diabetes: a four-year prospective study
Author(s) -
Tianpeng Zheng,
Attit Baskota,
Ying Gao,
Haoyu Tian,
Fan Yang
Publication year - 2014
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfu312
Subject(s) - medicine , microalbuminuria , dipeptidyl peptidase 4 , diabetes mellitus , proinflammatory cytokine , dipeptidyl peptidase 4 inhibitor , dipeptidyl peptidase , prospective cohort study , endocrinology , type 2 diabetes , inflammation , enzyme , chemistry , biochemistry
Recent evidence supports a protective role of dipeptidyl peptidase 4 (DPP4) inhibitors in lowering microalbuminuria (MAU) in diabetes but till now few studies have investigated the associations between DPP4 activity and MAU in nondiabetic Chinese individuals. This study tested whether DPP4 activity could predict new-onset MAU in Chinese without diabetes.
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