Open AccessEvaluation of bioartificial renal tubule device prepared with lifespan-extended human renal proximal tubular epithelial cells
Author(s) -
Akira Saitō,
Keigo Sawada,
Satoshi Fujimura,
Hajime Suzuki,
Takashi Hirukawa,
Rie Koga,
G. Kanai,
Hiroo Takahashi,
Takayo Miyakogawa,
Noriyuki Sanechika,
Masafumi Fukagawa,
Takatoshi Kakuta
Publication year - 2012
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr755
Subject(s) - medicine , renal tubule , proximal tubule , urology , kidney tubules , renal stem cell , kidney , pathology , endocrinology , microbiology and biotechnology , stem cell , progenitor cell , biology
Acute kidney injury (AKI), accompanied by the development of systemic inflammatory response syndrome and multiorgan dysfunction syndrome, is associated with a high risk of death. Bioartificial renal tubule device (BTD) is a cell therapy that improves the conditions common to artificial kidney recipients treated for kidney diseases. In this paper, we describe the establishment of BTD with lifespan-extended human renal proximal tubular epithelial cells.
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