Estimating individual glomerular volume in the human kidney: clinical perspectives
Author(s) -
Victor G. Puelles,
Monika Zimanyi,
Terence Samuel,
Michael D. Hughson,
R. N. Douglas-Denton,
John F. Bertram,
James A. Armitage
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr539
Subject(s) - medicine , kidney , renal function , clinical significance , muscle hypertrophy , identification (biology) , relevance (law) , pathology , cardiology , urology , botany , law , biology , political science
Measurement of individual glomerular volumes (IGV) has allowed the identification of drivers of glomerular hypertrophy in subjects without overt renal pathology. This study aims to highlight the relevance of IGV measurements with possible clinical implications and determine how many profiles must be measured in order to achieve stable size distribution estimates.
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