Open AccessHigher body mass index is associated with higher fractional creatinine excretion in healthy subjects
Author(s) -
Steef J. Sinkeler,
F. W. Visser,
Jan A. Krikken,
Coen A. Stegeman,
J.J. Homan van der Heide,
GJ Navis
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq850
Subject(s) - renal function , creatinine , medicine , urology , quartile , body mass index , excretion , kidney , kidney disease , endocrinology , confidence interval
Accurate glomerular filtration rate (GFR) measurement in normal to high range is important for epidemiological studies and workup for kidney donation. Creatinine-based equations perform poorly in this GFR range. Creatinine clearance (CrCl) provides a substitute, provided urine is collected accurately and tubular creatinine handling can be accounted for. The latter is poorly characterized in the normal GFR range.
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