Open AccessShort-term increase of glucose concentration in PDS results in extensive removal and high glycation level of vital proteins during continuous ambulatory peritoneal dialysis
Author(s) -
Ivana Pešić,
Gry H. Dihazi,
Gerhard A. Müller,
Olaf Jahn,
Moritz Hoffmann,
Marwa Eltoweissy,
Michael Koziolek,
Hassan Dihazi
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq793
Subject(s) - glycation , peritoneal dialysis , osmotic concentration , continuous ambulatory peritoneal dialysis , western blot , gel electrophoresis , dialysis , medicine , chromatography , dialysis tubing , proteome , andrology , endocrinology , biochemistry , chemistry , diabetes mellitus , membrane , gene
The effect of clearance of so-called middle- and high-molecular weight proteins on clinical outcome of patients treated by peritoneal dialysis is still a matter of debate. In our present study, we investigated the impact of short-time alteration of the glucose concentration and the osmolarity of the peritoneal dialysis solution (PDS) on protein removal.
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