Impact of iron treatment on immune effector function and cellular iron status of circulating monocytes in dialysis patients | Zendy

Thomas Sonnweber | Zendy; Igor Theurl | Zendy; M. Seifert | Zendy; Andrea Schroll | Zendy; Susanne Eder | Zendy; Gert Mayer | Zendy; G. Weiss | Zendy

Open Access

Impact of iron treatment on immune effector function and cellular iron status of circulating monocytes in dialysis patients

Author(s) -

Thomas Sonnweber,

Igor Theurl,

M. Seifert,

Andrea Schroll,

Susanne Eder,

Gert Mayer,

G. Weiss

Publication year - 2010

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfq483

Subject(s) - medicine , ferritin , hepcidin , monocyte , deferoxamine , immune system , tumor necrosis factor alpha , ferroportin , iron deficiency , dialysis , endocrinology , immunology , inflammation , ex vivo , anemia , in vivo , biology , microbiology and biotechnology

Iron is used as an adjunct therapy to treat anaemia in dialysis patients. However, iron may harbour detrimental effects in being a nutrient for invading pathogens or by modulating immune pathways. Thus, we prospectively studied the effects of iron treatment towards monocyte immune function.

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