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tions of urographic papillary abnormalities in patients with S hemoglobinopathies. Radiology 1974; 113: 59–63 21. Davis CJ, Jr. Mostofi FK, Sesterhenn IA. Renal medullary carcinoma. The seventh sickle cell nephropathy. Am J Surg Pathol 1995; 19: 1–11 22. Rathmell WK, Monk JP. High-dose-intensity MVAC for advanced renal medullary carcinoma: report of three cases and literature review. Urology 2008; 72: 659–663 23. Gupta AK, Kirchner KA, Nicholson R et al. Effects of alphathalassemia and sickle polymerization tendency on the urineconcentrating defect of individuals with sickle cell trait. J Clin Invest 1991; 88: 1963–1968 24. Derebail VK, Nachman PH, Key NS et al. High prevalence of sickle cell trait in African Americans with ESRD. J Am Soc Nephrol 2010; 21: 413–417 25. Ajayi AA, Kolawole BA. Sickle cell trait and gender influence type 2 diabetic complications in African patients. Eur J Intern Med 2004; 15: 312–315 26. Weiner DE. Public health consequences of chronic kidney disease. Clin Pharmacol Ther 2009; 86: 566–569 27. Zhang QL, Rothenbacher D. Prevalence of chronic kidney disease in population-based studies: systematic review. BMC Public Health 2008; 8: 117 28. Ansell D, Feehally J, Fogarty D et al. Eleventh Annual Report: The Renal Association UK Renal Registry, Bristol 2008 29. USRDS. United States Renal Data System for 2008 2008 30. John R, Webb M, Young A, Stevens PE. Unreferred chronic kidney disease: a longitudinal study. Am J Kidney Dis 2004; 43: 825–835 31. Reese PP, Hoo AC, Magee CC. Screening for sickle trait among potential live kidney donors: policies and practices in US transplant centers. Transpl Int 2008; 21: 328–331 32. BTS. United Kingdom Guidelines for Living Donor Kidney Transplantation 2005

When to start chronic dialysis: tunnel vision induced by numbers?