Open AccessMeropenem removal in critically ill patients undergoing sustained low-efficiency dialysis (SLED)
Author(s) -
Priya Deshpande,
Jiasheng Chen,
A. Gofran,
Mariana Murea,
Ladan Golestaneh
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq090
Subject(s) - meropenem , medicine , hemodialysis , dosing , dialysis , trough concentration , intensive care unit , anesthesia , trough level , peritoneal dialysis , surgery , urology , antibiotics , transplantation , tacrolimus , antibiotic resistance , microbiology and biotechnology , biology
The purpose of this study was to examine the removal of meropenem during an 8-h sustained low-efficiency dialysis (SLED) session. Using a minimum inhibitory concentration (MIC) = 2 microg/mL as our reference point, we also evaluated the therapeutic adequacy of dosing meropenem as 1 g every 12 h during SLED.
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