Open AccessHO-1 induction ameliorates experimental murine membranous nephropathy: anti-oxidative, anti-apoptotic and immunomodulatory effects
Author(s) -
C.-C. Wu,
KuoCheng Lu,
J.-S. Chen,
H.-Y. Hsieh,
ShihHua Lin,
Pauling Chu,
JiaYi Wang,
HueyKang Sytwu,
YuhFeng Lin
Publication year - 2008
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfn247
Subject(s) - copp , tbars , medicine , oxidative stress , proinflammatory cytokine , pharmacology , apoptosis , endocrinology , cytokine , heme oxygenase , immunology , lipid peroxidation , chemistry , inflammation , biochemistry , heme , enzyme
Therapeutic agents for membranous nephropathy (MN) remain ill-defined. Haeme oxygenase (HO)-1 is considered to play a protective role in various disorders. Here, we assessed the efficacy of HO-1 induction therapy for MN.
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