Open AccessPrediction of corticosteroid responsiveness based on fibroblast-specific protein 1 (FSP1) in patients with IgA nephropathy
Author(s) -
K. Harada,
Yasuhiro Akai,
Yasuo Yamaguchi,
Kumiko KIMURA,
Y. Nishitani,
Kimihiko Nakatani,
Masayuki Iwano,
Yoshihiro Saito
Publication year - 2008
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfn240
Subject(s) - medicine , corticosteroid , nephropathy , fibroblast , glomerulonephritis , immunology , endocrinology , kidney , in vitro , diabetes mellitus , biochemistry , chemistry
Corticosteroids are frequently used to treat patients with active IgA nephropathy (IgAN); however, there have been few reports describing factors that are predictive of the response to corticosteroid treatment. The purpose of this study is to determine the extent to which fibroblast-specific protein 1-positive (FSP1(+)) cells are predictive of corticosteroid responsiveness in patients with IgAN.
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