Open AccessSerum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy
Author(s) -
Sachiko Shimozato,
Yosio Hiki,
Hiroko Odani,
Kazuo Takahashi,
Koichiro Yamamoto,
Shigeki Sugiyama
Publication year - 2008
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfm913
Subject(s) - medicine , nephropathy , immunoglobulin a , glomerulonephritis , antibody , glycan , immunology , kidney disease , immunoglobulin g , kidney , endocrinology , diabetes mellitus , glycoprotein , microbiology and biotechnology , biology
Immunoglobulin A nephropathy (IgAN) is characterized by an aberrant structure of O-glycans in the IgA1 hinge region. Recently, under-galactosylated IgA1 has been found to be increased in Caucasian IgAN patients. Thus, we examined this in Japanese IgAN patients.
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