Open AccessThe cellular contribution to effluent potassium and its relation to free water transport during peritoneal dialysis
Author(s) -
Annemieke M. Coester,
D. G. Struijk,
Watske Smit,
Dirk R. de Waart,
Raymond T. Krediet
Publication year - 2007
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfm497
Subject(s) - peritoneal dialysis , medicine , urology , creatinine , ultrafiltration (renal) , dialysis , gastroenterology , endocrinology , biochemistry , chemistry
Aquaporin-1 (AQP-1) dysfunction is one of the valid theories for decreased free water transport (FWT) in long-term peritoneal dialysis (PD) ultrafiltration failure (UFF). We questioned whether apoptosis of peritoneal cells could be reflected in an increased release of cellular (CR) K(+) and explain AQP-1 dysfunction. If so, negative relationships between CR-K(+) and FWT would be expected. Therefore, we analysed CR-K(+) to total peritoneal K(+) removal, for possible relationships with FWT, the duration of PD, the presence of late UFF and effluent cancer antigen (CA) 125.
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