Open AccessAlbumin and hydroxyethyl starch 130 kDa/0.4 improve filter clearance and haemocompatibility in haemo- and plasmafiltration—an in vitro study
Author(s) -
J. Unger,
C. Haltern,
B. Dohmen,
Axel M. Gressner,
Christian GroßeSiestrup,
David A. Groneberg,
Rolf Rossaint
Publication year - 2005
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfh913
Subject(s) - hydroxyethyl starch , medicine , filtration (mathematics) , albumin , chromatography , clearance rate , haemolysis , biomedical engineering , hetastarch , hemodialysis , red blood cell , surgery , anesthesia , chemistry , immunology , mathematics , statistics
Apart from their standard applications, haemofiltration (HF) and plasmafiltration (PF) may provide helpful therapy for sepsis, multiple organ- and acute liver-failure. Some colloids cause either decreases or increases in blood cell agglomeration. We hypothesized that solutions which reduce cell aggregability may lead to both improved filter clearance and better haemocompatibility due to decreasing rates of clogged hollow fibres.
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