Hepatocyte growth factor and its receptor Met are induced in crescentic glomerulonephritis | Zendy

Teresa Rampino | Zendy; Marilena Gregorini | Zendy; Giovanni Camussi | Zendy; Pier Giulio Conaldi | Zendy; Grazia Soccio | Zendy; M. Maggio | Zendy; Antonella Bottelli | Zendy; Antonio Dal Canton | Zendy

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Hepatocyte growth factor and its receptor Met are induced in crescentic glomerulonephritis

Author(s) -

Teresa Rampino,

Marilena Gregorini,

Giovanni Camussi,

Pier Giulio Conaldi,

Grazia Soccio,

M. Maggio,

Antonella Bottelli,

Antonio Dal Canton

Publication year - 2005

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh740

Subject(s) - hepatocyte growth factor , transdifferentiation , endocrinology , peripheral blood mononuclear cell , medicine , podocyte , glomerulonephritis , growth factor , receptor , kidney , biology , microbiology and biotechnology , in vitro , stem cell , biochemistry , proteinuria

In experimental extracapillary glomerulonephritis (EG) podocytes migrate, proliferate and change phenotype, and play a pivotal role in crescent formation. Hepatocyte Growth Factor (HGF) is an injury-induced effector of tissue repair that causes cell migration, growth and transdifferentiation via its receptor Met.

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