A prospective proof of concept study of the efficacy of tacrolimus ointment on uraemic pruritus (UP) in patients on chronic dialysis therapy | Zendy

Dirk Kuypers | Zendy; K. Claes | Zendy; Pieter Evenepoel | Zendy; Bart Maes | Zendy; Yves Vanrenterghem | Zendy

Open Access

A prospective proof of concept study of the efficacy of tacrolimus ointment on uraemic pruritus (UP) in patients on chronic dialysis therapy

Author(s) -

Dirk Kuypers,

K. Claes,

Pieter Evenepoel,

Bart Maes,

Yves Vanrenterghem

Publication year - 2004

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh202

Subject(s) - medicine , tacrolimus , interquartile range , dialysis , prospective cohort study , adverse effect , visual analogue scale , rash , hemodialysis , surgery , transplantation

Uraemic pruritus (UP) is a serious symptom of chronic dialysis patients and patients with end-stage renal disease. UP causes skin damage, discomfort, sleeping disorders and diminished quality of life. Since UP is considered to be in part an immune-mediated inflammatory process, immunosuppressive drugs like tacrolimus may be beneficial.

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