Open AccessC-peptide and captopril are equally effective in lowering glomerular hyperfiltration in diabetic rats
Author(s) -
Björn Samnegård,
Stefan H. Jacobson,
BoLennart Johansson,
Karin Ekberg,
B. Isaksson,
J. Wahren,
M. SJÖQUIST
Publication year - 2004
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfh163
Subject(s) - medicine , glomerular hyperfiltration , captopril , endocrinology , diabetes mellitus , angiotensin converting enzyme , renal function , ace inhibitor , urinary system , urology , diabetic nephropathy , blood pressure
C-peptide has been shown to reduce glomerular hyperfiltration, glomerular hypertrophy and urinary albumin excretion in type 1 diabetes, but its effect has not been compared with that of an angiotensin-converting enzyme inhibitor (ACEI) in the early stage of renal involvement in diabetes.
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