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Successful local arterial urokinase infusion to reverse late postoperative venous thrombosis of a renal graft
Author(s) -
Pier Luigi Bedani,
Roberto Galeotti,
Giovanni Mugnani,
Isidoro Sciré Risichella,
Emanuela Rizzioli,
Adriano Verzola,
Luca Borgatti,
Simone Sala,
Costantina La Torre,
Giordano Stabellini,
P. Gilli
Publication year - 1999
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/14.9.2225
Subject(s) - medicine , urokinase , thrombosis , venous thrombosis , surgery , anesthesia
Graft renal vein thrombosis is fortunately rare, ranging between 1 and 4% of recipients . This event usually occurs in the early postoperative period and is associated with surgical complications, acute vascular rejection, and probably some immunosuppressive regimens, particularly OKT3, although the role of cyclosporin remains controversial . Unfortunately, acute thrombosis generally results in permanent graft loss, unless thrombectomy and postoperative anticoagulation are promptly started. \udThe occurrence of allograft vein thrombosis several months after kidney transplantation is infrequent. When the diagnosis is made early, streptokinase infusion can result in successful thrombolysis ]. \udWe present a case in which a partial renal vein thrombosis was successfully treated by combined intra-arterial and venous infusion of urokinase

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