Open AccessCD4dullCD8bright double-positive T-lymphocytes have a phenotype of granzyme Bpos CD8pos memory T-lymphocytes
Author(s) -
Rob J. Rentenaar
Publication year - 1999
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/14.6.1430
Subject(s) - cytotoxic t cell , granzyme b , granzyme a , immunology , phenotype , peripheral blood mononuclear cell , granzyme , medicine , cd8 , t lymphocyte , antigen , perforin , biology , in vitro , gene , biochemistry
T-lymphocytes that co-express CD4 and CD8 antigens may be found in small percentages in the peripheral blood of healthy individuals, and have a CD4brightCD8dull phenotype. CD4dullCD8bright T-lymphocytes have been found only in temporal association with some viral infections.
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