Open AccessPeritoneal protein loss in children with nephrotic syndrome during peritoneal dialysis
Author(s) -
Anthonius de Boer
Publication year - 1998
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/13.9.2348
Subject(s) - nephrotic syndrome , medicine , peritoneal dialysis , albumin , beta 2 microglobulin , proteinuria , endocrinology , glomerulonephritis , glomerular basement membrane , macroglobulin , renal function , kidney
The passage of proteins across the glomerular filtration barrier is mainly determined by the size of the protein. In nephrotic syndrome (NS) the glomerular permselectivity is affected, causing proteinuria. Some authors suggest the existence of a generalized basement membrane defect. The permeability characteristics of the peritoneal basement membrane in children with NS are not known.
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