Open AccessRenal and haemodynamic effects of amlodipine and nifedipine in hypertensive renal transplant recipients
Author(s) -
Gopalakrishnan VenkatRaman
Publication year - 1998
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/13.10.2612
Subject(s) - medicine , nifedipine , amlodipine , hemodynamics , cardiology , renal transplant , kidney , urology , blood pressure , calcium
Immunosuppressive treatment with cyclosporin A (CsA) improves the survival of renal allografts, but is associated with renal vasoconstriction and hypertension. Previous reports suggest that the calcium-channel blockers nifedipine and amlodipine may improve graft function in CsA-treated patients. We have compared the effects of amlodipine (5-10 mg once daily) and nifedipine retard (10-40 mg twice daily) on renal function and blood pressure in renal transplant recipients treated with CsA.
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