Open AccessDoes long-term treatment of renal anaemia with recombinant erythropoietin influence oxidative stress in haemodialysed patients?
Author(s) -
Olaf Sommerburg
Publication year - 1998
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/13.10.2583
Subject(s) - medicine , erythropoietin , malondialdehyde , oxidative stress , lipid peroxidation , endocrinology , hemodialysis , hemoglobin , gastroenterology , kidney disease
Patients with end-stage renal failure undergoing haemodialysis (HD) are exposed to oxidative stress. Increased levels of malondialdehyde (MDA) were demonstrated in plasma of uraemic patients, indicating accelerated lipid peroxidation (LPO) as a consequence of multiple pathogenetic factors. The aim of our investigation was to examine the role of renal anaemia in oxidative stress in HD patients.
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