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A series of novel alpha-beta chimeric oligonucleotides bearing anthraquinone-attached nucleobase at linker position, were synthesized as a triplex-forming oligonucleotide (TFO). Their ability to stabilize the alternate-stranded triple helix was investigated through the UV-melting experiments.

Synthesis and alternate-stranded triplex forming ability of novel - chimeric oligonucleotides bearing an intercalator-conjugated nucleobase