Open AccessA novel approach to the synthesis of oligodeoxyribonucleotide boranophosphates
Author(s) -
Takeshi Wada,
Mamoru Shimizu,
Natsuhisa Oka,
K. Saigo
Publication year - 2000
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/44.1.135
Subject(s) - guanine , cytosine , deoxyribonucleoside , thymine , chemistry , combinatorial chemistry , dna , biochemistry , nucleotide , gene
Deoxyribonucleoside 3'-boranophosphate derivatives including adenine, cytosine, guanine, and thymine bases were synthesized in good yields by the use of a new boranophosphorylation reaction. The reaction was found to be effective for the formation of internucleotidic boranophosphate linkages.
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