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Antisense oligonucleotides bearing an anthraquinone moiety at an internucleotide linkage were synthesized utilizing the stereoisomers of anthraquinone incorporated T-C dimer phosphoramidite derivatives. Some physicochemical properties of the anthraquinon bearing oligomers were investigated.

Synthesis and properties of novel antisense oligonucleotides bearing an anthraquinone moiety at an internucleotide linkage