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We report here kinetic analyses of the hydrolysis of DNA by the ATP-dependent DNase using a DNA-immobilized quartz-crystal microbalance (QCM), which enables in situ real-time monitoring both the binding of enzyme and the hydrolysis reaction on DNA strands, as mass changes.

Kinetic analyses of ATP-dependent deoxyribonuclease (DNase) reactions on a quartz-crystal microbalance