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Source/Description: Probe pMC27.7 is a 700 bp EcoRI fragment isolated from a cosmid (RS27) containing the HLA-G class I gene 1. The clone was derived from the MHC hemizygous B cell line, 3.1.0 2. pMC27.7 is found 17 kb 5' of the HLA-G 1 class I gene and approximately 100 kb from the HLA-A locus 2. The probe resides within a 2.0 kb nonpolymorphic HindUl fragment (35 unrelated individuals tested). Polymorphism: pMC27.7 crossreacts with a set of 4 polymorphic HindUl fragments, numbered 1 through 4 of 20, 15, 11, and 5 kb, respectively. Polymorphism is also detected with EcoRl but not with BglU.

D6S110 detects polymorphicHindIII fragments associated with individualHLA-Aclass I haplotypes