Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture | Zendy

Mieke Geens | Zendy; Anna Seriola | Zendy; Lise Barbé | Zendy; Josep Santaló | Zendy; Anna Veiga | Zendy; Kimberly Dee | Zendy; Lindsey Van Haute | Zendy; Karen Sermon | Zendy; Claudia Spits | Zendy

Open Access

Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture

Author(s) -

Mieke Geens,

Anna Seriola,

Lise Barbé,

Josep Santaló,

Anna Veiga,

Kimberly Dee,

Lindsey Van Haute,

Karen Sermon,

Claudia Spits

Publication year - 2016

Publication title -

molecular human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.143

H-Index - 122

eISSN - 1460-2407

pISSN - 1360-9947

DOI - 10.1093/molehr/gaw004

Subject(s) - biology , x inactivation , xist , dna methylation , induced pluripotent stem cell , epigenetics , genetics , histone , methylation , x chromosome , microbiology and biotechnology , gene expression , gene , embryonic stem cell

Does a preferential X chromosome inactivation (XCI) pattern exist in female human pluripotent stem cells (hPSCs) and does the pattern change during long-term culture or upon differentiation?

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom

About

About Careers Publisher Partners Contact Us Our institutional solutions Get Organisational Trial or Quote

Learn

FAQs Blog Terms of Use Privacy Policy

Download the Zendy App

Discover

Explore

Home ZAIA Blog