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Lamellar body counts in human amniotic fluid assist in the prediction of fetal lung maturity and can be performed rapidly and inexpensively by using the platelet channel of a hematology analyzer. We compared two analyzers for enumerating lamellar bodies. We tested 100 fresh amniotic fluid samples on both instruments. The lamellar body counts ranged from 3 to 364 × 103/μL (3−364 × 109/L) on one analyzer and from 3 to 195 × 103/μL (3−195 × 109/L) on the other. Statistical analysis showed excellent correlation (r = 0.99) yielding a regression equation of y = 3.91 + .467x. This analysis demonstrates that institutions will be faced with the challenge of establishing and incorporating instrumentspecific lamellar body reporting protocols and reference ranges that include the specific analyzer and method used.

Clinical Microscopy: Coulter STKSvsAbbott Cell-Dyn 3500 for Counting Lamellar Bodies in Amniotic Fluid