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Intensity-modulated radiation therapy (IMRT) is a widely accepted method for radiation treatment to provide a prescribed and uniform dose to the target volume and a minimum dose to normal tissues that is dependent on the IMRT software and the treatment machine. We examined the variation in IMRT dose prescription, treatment planning, dose recording, and dose delivery among cancer patients who were treated with different treatment planning systems at different medical institutions to assess variability in patient care.

journal of the national cancer institute

Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems