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Bortezomib is a selective and reversible inhibitor of the 26S proteasome that shows potent antitumor activity in vitro and in vivo against several human cancers of adulthood. No data are available on bortezomib activity against human pediatric neuroblastoma.

Effect of Bortezomib on Human Neuroblastoma Cell Growth, Apoptosis, and Angiogenesis