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The Human Genome Project announced recently that an international consortium of scientists has finished spelling out the entire genetic code of a species of yeast valuable to scientists and commonly used by bakers and brewers. This historic achievement, which comes nearly 4 years ahead of schedule and involved ordering 12 million units of DNA, marks the completion of the first full-sequence map of a eukaryotic, or complex, organism. Because humans also are eukaryotes who share basic cellular properties with this species of yeast, called Saccharomyces cerevisiae, the announcement had been anxiously awaited by biomedical researchers. The sequence map paves the way for science to undertake a comprehensive study of the yeast's genetic blueprint, assembling possibly within a few years the first full description of how a eukaryotic cell works, a longstanding goal of biology and medicine. "If the human sequence is biology's moonshot, then having the yeast sequence is like John Glenn orbiting the earth a few times," said Francis Collins, M.D., Ph.D., director of the National Institutes of Health's National Center for Human Genome Research, which supported American participation in the initiative.

Yeast's Value Rises as Scientists Map Its 6,000 Genes